Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50015369
TargetHigh affinity nerve growth factor receptor(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200372(US9227969, 1A | US9629836, 1A | US10011599, Exampl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of wild-type human partial length TRKA (G475 to G790 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585940(CHEMBL5090765)
Affinity DataIC50: 70nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585939(CHEMBL5094993)
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585939(CHEMBL5094993)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585942(CHEMBL5092411)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585943(CHEMBL5076921)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585941(CHEMBL5089865)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200455(US9227969, 84 | US10011599, Example 84)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200439(US9227969, 68 | US9629836, 68 | US10011599, Exampl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585938(CHEMBL5087942)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200425(US9227969, 52 | US10011599, Example 52)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585945(CHEMBL5088062)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200372(US9227969, 1A | US9629836, 1A | US10011599, Exampl...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200386(US9227969, 14 | US9629836, 14 | US10011599, Exampl...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585944(CHEMBL5086884)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50585946(CHEMBL5085569)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM200461(US9227969, 90 | US9629836, 90 | US10011599, Exampl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed