Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with all data for entry = 50015277
TargetATPase family AAA domain-containing protein 2B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  7.90nMAssay Description:Binding affinity to human ATAD2B bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  126nMAssay Description:Binding affinity to human BRD2 bromodomain 1 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  200nMAssay Description:Binding affinity to human BRD2 bromodomain 2 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  200nMAssay Description:Binding affinity to human BRD3 bromodomain 2 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human BRD9 bromodomain by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  200nMAssay Description:Binding affinity to human BRDT bromodomain 1 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human CECR2 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <3.16E+3nMAssay Description:Binding affinity to human EP300 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNucleosome-remodeling factor subunit BPTF(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human FALZ bromodomain by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human PBRM1 bromodomain 5 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human PCAF bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetProbable global transcription activator SNF2L2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <3.16E+3nMAssay Description:Binding affinity to human SMARCA2 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  158nMAssay Description:Binding affinity to human TAF1 bromodomain 2 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain and WD repeat-containing protein 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human WDR9 bromodomain 2 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to ATAD2 bromodomain (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50: 14nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584941(CHEMBL5077167)
Affinity DataIC50: 32nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584943(CHEMBL5086059)
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584943(CHEMBL5086059)
Affinity DataIC50: 41nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 50nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584938(CHEMBL5086260)
Affinity DataIC50: 78nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584938(CHEMBL5086260)
Affinity DataIC50: 79nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 79nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 100nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 126nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2A BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50464128(CHEMBL4206758)
Affinity DataIC50: 158nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584936(CHEMBL5074983)
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50464128(CHEMBL4206758)
Affinity DataIC50: 200nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584936(CHEMBL5074983)
Affinity DataIC50: 210nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584939(CHEMBL5084768)
Affinity DataIC50: 251nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50464128(CHEMBL4206758)
Affinity DataIC50: 251nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584939(CHEMBL5084768)
Affinity DataIC50: 280nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584941(CHEMBL5077167)
Affinity DataIC50: 300nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584940(CHEMBL5092181)
Affinity DataIC50: 370nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584935(CHEMBL5083025)
Affinity DataIC50: 398nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584937(CHEMBL5093167)
Affinity DataIC50: 398nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584940(CHEMBL5092181)
Affinity DataIC50: 398nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584935(CHEMBL5083025)
Affinity DataIC50: 420nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584937(CHEMBL5093167)
Affinity DataIC50: 440nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50: 501nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2A BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50: 501nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584938(CHEMBL5086260)
Affinity DataIC50: 501nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50: 501nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
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