Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50016432
TargetProstaglandin D2 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50594971(TREPROSTINIL | CHEBI:50861 | Treprostinil | Trespr...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human DP1 expressed in human 1321N1 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin D2 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human DP1 expressed in human 1321N1 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstacyclin receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50594971(TREPROSTINIL | CHEBI:50861 | Treprostinil | Trespr...)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human IP expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of cA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstacyclin receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human IP expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of cA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50594971(TREPROSTINIL | CHEBI:50861 | Treprostinil | Trespr...)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human EP2 expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataEC50:  2.09E+3nMAssay Description:Agonist activity at human EP2 expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50594971(TREPROSTINIL | CHEBI:50861 | Treprostinil | Trespr...)
Affinity DataEC50:  285nMAssay Description:Agonist activity at human EP1 expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human EP1 expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed