Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50017589
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 170nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603134(CHEMBL5202967)
Affinity DataIC50: 240nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603133(CHEMBL5190525)
Affinity DataIC50: 460nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603135(CHEMBL5178161)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603152(CHEMBL5170772)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603150(CHEMBL5176974)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603148(CHEMBL5208533)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603151(CHEMBL5171053)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603140(CHEMBL5209481)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603149(CHEMBL5172623)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603154(CHEMBL5203602)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603142(CHEMBL5192799)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603139(CHEMBL5188663)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603138(CHEMBL5202748)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603161(CHEMBL5178951)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603155(CHEMBL5176381)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603159(CHEMBL5187485)
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603147(CHEMBL5175443)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603156(CHEMBL5172881)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603143(CHEMBL5171351)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603145(CHEMBL5208115)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603137(CHEMBL5194068)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603153(CHEMBL5190081)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603160(CHEMBL5207943)
Affinity DataIC50: 4.74E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603158(CHEMBL5179446)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603141(CHEMBL5183915)
Affinity DataIC50: 5.36E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603146(CHEMBL5199583)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603144(CHEMBL5202723)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603162(CHEMBL5195683)
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603163(CHEMBL5183898)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603157(CHEMBL5201381)
Affinity DataIC50: 6.97E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603168(CHEMBL5175506)
Affinity DataIC50: 8.05E+3nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 9(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603134(CHEMBL5202967)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of GLUT9 (unknown origin) expressed in HEK293T cells assessed as inhibition of uric acid-induced current by whole cell patch clamp techniq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603164(CHEMBL5204323)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603167(CHEMBL5202543)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603169(CHEMBL5184930)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603166(CHEMBL5191628)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603165(CHEMBL5208873)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603133(CHEMBL5190525)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603134(CHEMBL5202967)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603135(CHEMBL5178161)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603134(CHEMBL5202967)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603133(CHEMBL5190525)
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603135(CHEMBL5178161)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed