Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50016864
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PARP1 by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 60 mins by microplate assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50096200(CHEMBL3593806)
Affinity DataIC50: 13nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 50nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 60 mins by microplate assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TNKS1/TNKS2 (unknown origin) by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50232347(CHEMBL4089840)
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 379nMAssay Description:Inhibition of BRD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 400nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 440nMAssay Description:Inhibition of BRD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 600nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 800nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50232347(CHEMBL4089840)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50103503(CHEMBL2393130 | US11117865, Compound RVX-208)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50232347(CHEMBL4089840)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50096142(CHEMBL3593985)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597851(CHEMBL5206726)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50096146(CHEMBL3593990)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed