Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50015571
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587599(CHEMBL5087453 | US11661419, Example 53 | US2023028...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587592(CHEMBL5090091 | US11661419, Example 7 | US20230280...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587593(CHEMBL5088468 | US11661419, Example 11 | US2023028...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587596(CHEMBL5086824 | US11661419, Example 36 | US2023028...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587590(CHEMBL5084598 | US11661419, Example 1 | US20230280...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587598(CHEMBL5074957 | US11661419, Example 46 | US2023028...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587597(CHEMBL5079033 | US11661419, Example 39 | US2023028...)
Affinity DataIC50: 8nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587594(CHEMBL5082562 | US11661419, Example 18 | US2023028...)
Affinity DataIC50: 9nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587599(CHEMBL5087453 | US11661419, Example 53 | US2023028...)
Affinity DataIC50: 10nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587592(CHEMBL5090091 | US11661419, Example 7 | US20230280...)
Affinity DataIC50: 13nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587591(CHEMBL5080834 | US11661419, Example 3 | US20230280...)
Affinity DataIC50: 16nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587593(CHEMBL5088468 | US11661419, Example 11 | US2023028...)
Affinity DataIC50: 34nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587590(CHEMBL5084598 | US11661419, Example 1 | US20230280...)
Affinity DataIC50: 39nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587598(CHEMBL5074957 | US11661419, Example 46 | US2023028...)
Affinity DataIC50: 47nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587597(CHEMBL5079033 | US11661419, Example 39 | US2023028...)
Affinity DataIC50: 82nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587594(CHEMBL5082562 | US11661419, Example 18 | US2023028...)
Affinity DataIC50: 91nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587596(CHEMBL5086824 | US11661419, Example 36 | US2023028...)
Affinity DataIC50: 96nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587591(CHEMBL5080834 | US11661419, Example 3 | US20230280...)
Affinity DataIC50: 113nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587595(CHEMBL5083169 | US11661419, Example 23 | US2023028...)
Affinity DataIC50: 124nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50587595(CHEMBL5083169 | US11661419, Example 23 | US2023028...)
Affinity DataIC50: 304nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed