Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50015477
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 44nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 61nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 76nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 84nMAssay Description:Inhibition of BRD4 BD1/BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 92nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 98nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 180nMAssay Description:Inhibition of BRD4 BD1/BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 185nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 185nMAssay Description:Inhibition of BRDT BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 193nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 207nMAssay Description:Inhibition of BRDT BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 230nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRDT BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRDT BD2 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50587013(CHEMBL5091216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)