Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50016412
TargetCoagulation factor X(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50594756(CHEMBL5201486)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human FXa using chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor X(Mouse)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50559550(CHEMBL4746164)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of mouse FXaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor X(Mouse)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50594755(CHEMBL5175994)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of mouse FXaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50112086(CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor X(Mouse)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50594754(CHEMBL5181169)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse FXaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50079890(CHEMBL3415215)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50500060(CHEMBL3740288)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate incubated for 10 mins by fluorescence based microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50079895(CHEMBL3415211)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50079937(CHEMBL3415064)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor X(Mouse)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50084617(YM-60828 | ((7-carbamimidoyl-naphthalen-2-ylmethyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse FXaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50079936(CHEMBL3415065)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50079896(CHEMBL3415210)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate incubated for 10 mins by fluorescence based microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor VII(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM14593(CHEMBL77076 | 3-amino-5-[1-({[(4-carbamimidoylphen...)
Affinity DataIC50: 16nMAssay Description:Inhibition of tissue factor VIIa complex (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50085328(Phosphoric acid mono-[4-(6-methylamino-purin-9-yl)...)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at P2Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50104014(Phosphoric acid mono-[3-(2-chloro-6-methylamino-pu...)
Affinity DataIC50: 840nMAssay Description:Antagonist activity at P2Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50104026(Phosphoric acid mono-[3-(6-methylamino-purin-9-yl)...)
Affinity DataIC50: 1.09E+3nMAssay Description:Antagonist activity at P2Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 1(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50118229(MRS 2179 | CHEMBL129841)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of P2X1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at P2Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor XII(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50146944(CHEMBL3765536)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of factor XIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 3(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50118229(MRS 2179 | CHEMBL129841)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of P2X3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProthrombin(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50594753(CHEMBL5204945)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCoagulation factor X(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50358256(CHEMBL168946)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to FXa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed