Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50018413
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608145(CHEMBL5282677)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608149(CHEMBL5273669)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608147(CHEMBL5280395)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608148(CHEMBL5290077)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608146(CHEMBL5281180)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50051913(N*6*-(2,5-Dimethoxy-benzyl)-N*6*-methyl-pyrido[2,3...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50389704(CHEMBL2070081 | US9518026, Example 9 | US9765037, ...)
Affinity DataIC50: 400nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608151(CHEMBL5287465)
Affinity DataIC50: 495nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608150(CHEMBL5268869)
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50051915(N*6*-(2,5-Dimethoxy-benzyl)-pyrido[2,3-d]pyrimidin...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM416558(US10307425, Example 24 | US10632122, Example 24)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPurine nucleoside phosphorylase(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50608144(CHEMBL5283969)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed