Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016858
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3758(N-(3-Bromophenyl)-6-methoxy-1H-pyrimido[4,5-b]indo...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597827(CHEMBL5184038)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597830(CHEMBL5183413)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597828(CHEMBL5187154)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597822(CHEMBL5175208)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597826(CHEMBL5169624)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5323(1-[3-(4-methylpiperazin-1-yl)propyl]-3-[5-(thiophe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597829(CHEMBL5171763)
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597820(CHEMBL423224)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597823(CHEMBL5172665)
Affinity DataIC50: 31nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5322(1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...)
Affinity DataIC50: 38nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597824(CHEMBL5202879)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5324(dimethyl(3-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 64nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3744(N-(3-bromophenyl)-5H-pyrimido[5,4-b]indol-4-amine ...)
Affinity DataIC50: 72nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597825(CHEMBL5199108)
Affinity DataIC50: 84nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5320(1-[2-(piperidin-1-yl)ethyl]-3-[5-(thiophen-3-yl)py...)
Affinity DataIC50: 111nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5319(dimethyl(2-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 115nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5318(3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole | 3-(5...)
Affinity DataIC50: 126nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3746(N-benzyl-5H-pyrimido[5,4-b]indol-4-amine | Pyrimid...)
Affinity DataIC50: 460nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4000(N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 850nMAssay Description:Inhibition of EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597831(CHEMBL5182427)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of p60 c-src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3985(3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597821(CHEMBL309276)
Affinity DataIC50: 1.62E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3750(dimethyl(2-{5H-pyrimido[5,4-b]indol-4-ylamino}ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3749(N-cyclohexyl-5H-pyrimido[5,4-b]indol-4-amine | Pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597819(CHEMBL5205062)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4032(2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597832(CHEMBL5184360)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed