Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015217
TargetCytochrome P450 2D6(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CYP2D6 preincubated for 5 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 5 nM 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 1 nM 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of full length H-RNAase L expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate incubated for 15 min in presence of 20 nM 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50362886(VITEXIN)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 2.64E+5nMAssay Description:Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM23448(butyl 4-hydroxybenzoate | Nipabutyl | BUTYLPARABEN...)
Affinity DataIC50: 2.40E+6nMAssay Description:Inhibition of recombinant full length H-RNAase L (1 to 741 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed