Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50016410
TargetTyrosine-protein kinase Blk(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of full-length wild-type BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594747(Pirtobrutinib | Loxo-305 | LOXO-305 | LY-3527727 |...)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594747(Pirtobrutinib | Loxo-305 | LOXO-305 | LY-3527727 |...)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50546200(Vecabrutinib | Sns-062 | BIIB-062 | BSK-4841 | FP-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human BTK C481S mutant measured by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594227(CHEMBL5169992)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594227(CHEMBL5169992)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50546200(Vecabrutinib | Sns-062 | BIIB-062 | BSK-4841 | FP-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human BTK measured by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM36516(4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morp...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594748(CHEMBL5202670)
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length wild-type BTK (unknown origin) measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM36516(4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morp...)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK C481S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 16nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594748(CHEMBL5202670)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK C481S mutant (unknown origin) measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 32nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 44nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 46nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 50nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 77nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50: 88nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 116nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Tec(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 126nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase TXK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 368nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 991nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594745(CHEMBL5187554)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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