Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50016628
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of rat muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentrati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of rat muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentrati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 228nMAssay Description:Inhibition of rat muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentrati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 525nMAssay Description:Inhibition of rat muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentrati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of rat muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using cocktail of isoform-specific probe substrateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 724nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using cocktail of isoform-specific probe substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using cocktail of isoform-specific probe substrateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using cocktail of isoform-specific probe substrateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentra...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholi...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human muscarinic acetylcholine M1 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholi...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat muscarinic acetylcholine M5 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat muscarinic acetylcholine M3 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat muscarinic acetylcholine M1 receptor expressed in CHO cells co-expressing Gqi5 preincubated with compound followed by acetylcholine...More data for this Ligand-Target Pair
