Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50014773
TargetSpike glycoprotein(2019-nCoV)
University of California San Francisco (Ucsf)

Curated by ChEMBL
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ))
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SARS-COV2 ACE2 binding to spike glycoprotein S RBD domain preincubated for 31 mins with RBD followed by protein addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of California San Francisco (Ucsf)

Curated by ChEMBL
LigandPNGBDBM152157(US8987474, Hematin)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant SARS-COV2 His-tagged S-RBD binding to recombinant human ACE2 expressed in HEK293T cells incubated for 0.5 hrs by alpha scre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of California San Francisco (Ucsf)

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant SARS-COV2 His-tagged S-RBD binding to recombinant human ACE2 expressed in HEK293T cells incubated for 0.5 hrs by alpha scre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
University of California San Francisco (Ucsf)

Curated by ChEMBL
LigandPNGBDBM50416875(CINACALCET | AMG-073 | AMG073 HCL | CINACALCET HYD...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of recombinant human ACE2 using MCA-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH as substrate preincubated for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed