Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50015560
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.640nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 14nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 80nMAssay Description:Binding affinity to GST-tagged AR ligand binding domain (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 170nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587510(CHEMBL5076873)
Affinity DataIC50: 410nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587535(CHEMBL5082962)
Affinity DataIC50: 470nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 480nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP assessed as decrease in PSA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587537(CHEMBL5087488)
Affinity DataIC50: 610nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 750nMAssay Description:Binding affinity to GST-tagged AR ligand binding domain (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587509(CHEMBL5071682)
Affinity DataIC50: 780nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587538(CHEMBL5079698)
Affinity DataIC50: 890nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587508(CHEMBL5093730)
Affinity DataIC50: 920nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587533(CHEMBL5088635)
Affinity DataIC50: 940nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587536(CHEMBL5087976)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM21150(7-(benzyloxy)-4-(trifluoromethyl)-2H-chromen-2-one...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587507(CHEMBL5079200)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587511(CHEMBL5077637)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587539(CHEMBL5094619)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 1.66E+3nMAssay Description:Binding affinity to GST-tagged AR ligand binding domain (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587549(CHEMBL5083886)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587534(CHEMBL5084126)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP assessed as decrease in PSA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587506(CHEMBL5081630)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587541(CHEMBL5091168)
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587547(CHEMBL5094528)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587540(CHEMBL5078938)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587543(CHEMBL5071912)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587545(CHEMBL5076252)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587544(CHEMBL5091684)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587542(CHEMBL5087790)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587550(CHEMBL5092095)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587546(CHEMBL5083402)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587551(CHEMBL5091707)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587548(CHEMBL5094403)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587513(CHEMBL5076618)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587526(CHEMBL5079827)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587517(CHEMBL5085150)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587518(CHEMBL5069607)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587519(CHEMBL5088995)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587520(CHEMBL5078776)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587521(CHEMBL5079893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587522(CHEMBL5089532)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587523(CHEMBL5094463)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587524(CHEMBL5084639)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587525(CHEMBL5083411)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587512(CHEMBL5088483)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587527(CHEMBL5074385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587528(CHEMBL5076847)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
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