Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50015553
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50217448(trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]b...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587459(CHEMBL5092295)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM81356(PF-3845, 10 | US20240308985, Comparator TableD2.2)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587467(CHEMBL5094294)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587464(CHEMBL5074748)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587466(CHEMBL5076329)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587463(CHEMBL5082839)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587452(CHEMBL5089361)
Affinity DataIC50: 7nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587459(CHEMBL5092295)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587457(CHEMBL5083307)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587452(CHEMBL5089361)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587465(CHEMBL5093204)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587466(CHEMBL5076329)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587467(CHEMBL5094294)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587464(CHEMBL5074748)
Affinity DataIC50: 18nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587461(CHEMBL5086741)
Affinity DataIC50: 23nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587465(CHEMBL5093204)
Affinity DataIC50: 25nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587463(CHEMBL5082839)
Affinity DataIC50: 31nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587457(CHEMBL5083307)
Affinity DataIC50: 102nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587456(CHEMBL5089943)
Affinity DataIC50: 110nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587455(CHEMBL5075955)
Affinity DataIC50: 130nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587458(CHEMBL5082030)
Affinity DataIC50: 140nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587461(CHEMBL5086741)
Affinity DataIC50: 142nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587453(CHEMBL5081733)
Affinity DataIC50: 160nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587462(CHEMBL5083500)
Affinity DataIC50: 170nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587458(CHEMBL5082030)
Affinity DataIC50: 180nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587454(CHEMBL5088092)
Affinity DataIC50: 220nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587460(CHEMBL5072765)
Affinity DataIC50: 330nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587451(CHEMBL5076877)
Affinity DataIC50: 510nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587460(CHEMBL5072765)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587462(CHEMBL5083500)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FAAH using N-(6-methoxypyridin-3-yl)octanamide as a substrate assessed as reduction in 6-methoxypyridin-3-amine formation by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587456(CHEMBL5089943)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587455(CHEMBL5075955)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587453(CHEMBL5081733)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587454(CHEMBL5088092)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
California State University

Curated by ChEMBL
LigandPNGBDBM50587451(CHEMBL5076877)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human sEH using cyano(6-methoxynaphthalen-2-yl)methyl((3-phenyloxiran-2-yl)methyl)carbonate as a substrate assessed as reduction in 6-m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed