Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50018514
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  34nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  49nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataEC50:  68nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  73nMAssay Description:Partial agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  79nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  125nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataEC50:  166nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  216nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  422nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  578nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  649nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  666nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  858nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  883nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  1.36E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.88E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  3.24E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataEC50:  3.59E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  4.14E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataEC50:  5.78E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataEC50:  6.23E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  6.90E+3nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  7.18E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  7.95E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataEC50:  9.38E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed