Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50014772
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579953(CHEMBL5085104)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579951(CHEMBL5078349)
Affinity DataEC50:  202nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579950(CHEMBL5080233)
Affinity DataEC50:  189nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579949(CHEMBL5084034)
Affinity DataEC50:  154nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579948(CHEMBL5080666)
Affinity DataEC50:  160nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579953(CHEMBL5085104)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579948(CHEMBL5080666)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579949(CHEMBL5084034)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579951(CHEMBL5078349)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579950(CHEMBL5080233)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  2.09E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  3.17E+3nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579953(CHEMBL5085104)
Affinity DataKi:  4.27E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579953(CHEMBL5085104)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  6.11E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.77E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579951(CHEMBL5078349)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579948(CHEMBL5080666)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579949(CHEMBL5084034)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579950(CHEMBL5080233)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579949(CHEMBL5084034)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579948(CHEMBL5080666)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579951(CHEMBL5078349)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579950(CHEMBL5080233)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed