Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50016626
TargetTyrosine-protein kinase JAK1(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human GST-fused JAK1 (845 to 1142 residues) expressed in Sf9 cells at varying concentrations of ATP by competitive binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596199(CHEMBL5199899)
Affinity DataIC50: 72nMAssay Description:Inhibition of JAK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596198(CHEMBL5175927)
Affinity DataIC50: 97nMAssay Description:Inhibition of JAK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596197(CHEMBL5202702)
Affinity DataIC50: 107nMAssay Description:Inhibition of JAK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged JAK2 (808 to end residues) expressed in baculovirus infected Sf21 cells at varying concentrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596200(CHEMBL5196293)
Affinity DataIC50: 386nMAssay Description:Inhibition of JAK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596198(CHEMBL5175927)
Affinity DataIC50: 784nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596199(CHEMBL5199899)
Affinity DataIC50: 839nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596197(CHEMBL5202702)
Affinity DataIC50: 959nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50596200(CHEMBL5196293)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed