Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50016620
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...)
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataIC50: 7.36E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50596182(CHEBI:64021 | CHEMBL3526436)
Affinity DataIC50: 8.54E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50239972(CHEBI:6794 | Metaraminol)
Affinity DataIC50: 9.81E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50480261(CHEBI:4853 | NSC-26665 | ESCULIN)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM34571(6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM43662(SMR000059060 | 3-phenyl-7-propan-2-yloxychromen-4-...)
Affinity DataIC50: 2.55E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50596183(CHEBI:17381 | CHEMBL1235151)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US8618147, ISO-1 | methyl 2-(3-(4-h...)
Affinity DataKi:  4.35E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50596182(CHEBI:64021 | CHEMBL3526436)
Affinity DataKi:  6.18E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50239972(CHEBI:6794 | Metaraminol)
Affinity DataKi:  7.71E+4nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM50480261(CHEBI:4853 | NSC-26665 | ESCULIN)
Affinity DataKi:  1.43E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Wuhan University

Curated by ChEMBL
LigandPNGBDBM34571(6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...)
Affinity DataKi:  1.84E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate addition by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed