Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50015539
TargetAmyloid-beta precursor protein(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587301(CHEMBL5094225)
Affinity DataKd:  5.16E+4nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587299(CHEMBL5077020)
Affinity DataKd:  1.55E+6nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587291(CHEMBL5092830)
Affinity DataKd:  1.20E+7nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  0.631nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587293(CHEMBL5090291)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50533199(CHEMBL4527011)
Affinity DataKi:  2nMAssay Description:Antagonist activity at histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587292(CHEMBL5082819)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587298(CHEMBL5092241)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50247053(Tiprolisant | 1-(3-(3-(4-chlorophenyl)propoxy)prop...)
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587300(CHEMBL5093401)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587294(CHEMBL5092036)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587296(CHEMBL5079959)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587297(CHEMBL5086337)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587299(CHEMBL5077020)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587302(CHEMBL5080274)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50247053(Tiprolisant | 1-(3-(3-(4-chlorophenyl)propoxy)prop...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587301(CHEMBL5094225)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587295(CHEMBL5087354)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587291(CHEMBL5092830)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587287(CHEMBL5081279)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587288(CHEMBL5078493)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587289(CHEMBL5085646)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50587290(CHEMBL5083150)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells incubated for 90 mins by competitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed