Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50014959
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581526(CHEMBL5077278)
Affinity DataKd:  9.33E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581527(CHEMBL5072948)
Affinity DataKd:  3.01E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581528(CHEMBL5070147)
Affinity DataKd:  1.81E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581529(CHEMBL5072338)
Affinity DataKd:  8.21E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581531(CHEMBL5074808)
Affinity DataKd:  3.52E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581532(CHEMBL5091830)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581533(CHEMBL5090828)
Affinity DataKd:  7.30E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581534(CHEMBL1738948)
Affinity DataKd:  5.53E+6nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  2.15E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant in presence of Nonyl-mal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)