Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50018408
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50: 1.70nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50: 2.60nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50499377(CHEMBL3735194)
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608112(CHEMBL5283802)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608113(CHEMBL5267367)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608114(CHEMBL5290660)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608115(CHEMBL5288199)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608116(CHEMBL5269658)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517966(CHEMBL4587811)
Affinity DataIC50: 21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517974(CHEMBL4457733)
Affinity DataIC50: 21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517960(CHEMBL4447225)
Affinity DataIC50: 21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517959(CHEMBL4536115)
Affinity DataIC50: 21nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517967(CHEMBL4443828)
Affinity DataIC50: 27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517958(CHEMBL4470236)
Affinity DataIC50: 27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50517962(CHEMBL4462318)
Affinity DataIC50: 27nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608110(CHEMBL5273741)
Affinity DataIC50: 32nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608109(CHEMBL5274305)
Affinity DataIC50: 37nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608111(CHEMBL5269307)
Affinity DataIC50: 43nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50608118(CHEMBL5287460)
Affinity DataIC50: 52nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlkaline phosphatase, germ cell type(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608127(CHEMBL5286891)
Affinity DataIC50: 75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlkaline phosphatase, germ cell type(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608126(CHEMBL5283595)
Affinity DataIC50: 75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlkaline phosphatase, germ cell type(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608128(CHEMBL5290778)
Affinity DataIC50: 75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAlkaline phosphatase, germ cell type(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608129(CHEMBL5286403)
Affinity DataIC50: 75nMAssay Description:Inhibition of human germ cell alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608117(CHEMBL5288269)
Affinity DataIC50: 77nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50570877(CHEMBL4848882)
Affinity DataIC50: 130nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608130(CHEMBL5271772)
Affinity DataIC50: 130nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608122(CHEMBL5291477)
Affinity DataIC50: 150nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50010462(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
Affinity DataIC50: 160nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase mTOR(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608120(CHEMBL5286229)
Affinity DataIC50: 190nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50608119(CHEMBL5278588)
Affinity DataIC50: 197nMAssay Description:Inhibition of PI3K gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50162147(1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50: 360nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 380nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 600nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50608120(CHEMBL5286229)
Affinity DataIC50: 980nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50506691(CHEMBL4515319)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608108(CHEMBL5284920)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50506690(CHEMBL4541986)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human DOT1L (1 to 416 residues) expressed in Escherichia coli (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608121(CHEMBL5276080)
Affinity DataIC50: 1.93E+3nMAssay Description:Displacement of biotinylated Bim peptide from Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608107(CHEMBL5286675)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50608125(CHEMBL5285843)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of human G9a expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50608124(CHEMBL5284371)
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50608123(CHEMBL5281928)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of human G9a expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed