Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50014268
TargetSerine/threonine-protein kinase pim-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 30nMAssay Description:Inhibition of PIM1 (unknown origin) in presence of 1 mM ATP without preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 34nMAssay Description:Inhibition of PIM1 (unknown origin) in presence of 1 mM ATP with preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 36nMAssay Description:Inhibition of CDC7 in human SW-620 cells assessed as reduction in phosphorylation of MCM2 at Ser40 residue incubated for 48 hrs by Western blot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 53nMAssay Description:Inhibition of CDC7 in human SW-620 cells assessed as reduction in phosphorylation of MCM2 at Ser53 residue incubated for 48 hrs by Western blot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 189nMAssay Description:Inhibition of GSK3alpha (unknown origin) in presence of 1 mM ATP without preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 206nMAssay Description:Inhibition of CLK1 (unknown origin) in presence of 1 mM ATP with preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 212nMAssay Description:Inhibition of CLK1 (unknown origin) in presence of 1 mM ATP without preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 227nMAssay Description:Inhibition of CLK2 (unknown origin) in presence of 1 mM ATP with preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 251nMAssay Description:Inhibition of GSK3alpha (unknown origin) in presence of 1 mM ATP with preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50574282(CHEMBL4868568)
Affinity DataIC50: 270nMAssay Description:Inhibition of CLK2 (unknown origin) in presence of 1 mM ATP without preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed