Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50015650
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588193(CHEMBL586053)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of DENV NS2B/NS3 protease transfected in human Huh-7 cells using 7-amino-4-methylcoumarin (AMC) fluorophore-linked peptide substrate Boc-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525245(CHEMBL1980535)
Affinity DataEC50:  8.50E+3nMAssay Description:Inhibition of DENV NS2B/NS3 protease transfected in human Huh-7 cells treated for 3 days by nano-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588195(CHEMBL5188858)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of DENV NS2B/NS3 proMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588184(CHEMBL5206054)
Affinity DataIC50: 15nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588185(CHEMBL5205657)
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50185449(panduratin A | (-)-panduratin A | CHEMBL379110)
Affinity DataIC50: 57nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 3 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 4 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 2 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 1 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588181(CHEMBL5194226)
Affinity DataIC50: 380nMAssay Description:Inhibition of DENV-2 NS2B/NS3 protease expressed in Escherichia coli XL1 using Boc-GRR-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588175(CHEMBL5177343)
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using fluorophore-tagged Bz-nKRR-AMC as substrate preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 3 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 2 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 1 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 4 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50509461(CHEMBL4440832)
Affinity DataIC50: 990nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588176(CHEMBL5172831)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using fluorophore-tagged Bz-nKRR-AMC as substrate preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50482((5Z)-5-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of Dengue Virus 3 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50482((5Z)-5-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of Dengue Virus 2 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50482((5Z)-5-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of Dengue Virus 1 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50482((5Z)-5-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of Dengue Virus 4 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50509461(CHEMBL4440832)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588177(CHEMBL5192980)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588180(CHEMBL5190426)
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of DENV-2 NS2bNS3 proMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50523756(ERYTHROSINE SODIUM | BDBM50588194)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of DENV2 His tagged NS2B (48 to 95 residues)/NS3 (1 to 185 residues) protein protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588178(CHEMBL5176286)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588178(CHEMBL5176286)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588179(CHEMBL5202407)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM47632(cid_5718631 | (2Z)-1-ethyl-2-[(E)-3-(1-ethyl-2-ben...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525247(CHEMBL4533598)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588177(CHEMBL5192980)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM152653(4-(1,3-Dioxoisoindolin-2-yl)-N-(4-ethylphenyl)benz...)
Affinity DataIC50: 4.82E+4nMAssay Description:Inhibition of DENV2 NS2B/NS3 protease using Bz-Nle-Lys-Arg-Arg-AMC as substrate incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50525247(CHEMBL4533598)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588182(CHEMBL5199579)
Affinity DataIC50: 2.14E+5nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-MCA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588183(CHEMBL4456898)
Affinity DataIC50: 2.57E+5nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-MCA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588190(CHEMBL5170076)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588190(CHEMBL5170076)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to DENV2 NS2B/NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50513213(CHEMBL3344303)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to DENV2 NS2B/NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50513213(CHEMBL3344303)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588187(CHEMBL5194503)
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity to DENV2 NS2B/NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588187(CHEMBL5194503)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50513887(CHEMBL4458555)
Affinity DataKi:  1.21E+4nMAssay Description:Binding affinity to DENV2 NS2B/NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50513887(CHEMBL4458555)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588189(CHEMBL5206550)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity to DENV2 NS2B/NS3 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50588189(CHEMBL5206550)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
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