Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50014266
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM117012(US8637532, 739)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574277(CHEMBL4871106)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM117012(US8637532, 739)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574274(CHEMBL4860970)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574278(CHEMBL4854144)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574276(CHEMBL4846712)
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574271(CHEMBL4876446)
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM116525(US8637532, 211)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574275(CHEMBL4856439)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574270(CHEMBL4855657)
Affinity DataIC50: 14nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM116525(US8637532, 211)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574273(CHEMBL4871853)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574268(CHEMBL4851020)
Affinity DataIC50: 22nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574272(CHEMBL4875416)
Affinity DataIC50: 23nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574272(CHEMBL4875416)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574278(CHEMBL4854144)
Affinity DataIC50: 44nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574269(CHEMBL4857965)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574268(CHEMBL4851020)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574270(CHEMBL4855657)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574279(CHEMBL4869229)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574274(CHEMBL4860970)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574275(CHEMBL4856439)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574277(CHEMBL4871106)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574271(CHEMBL4876446)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574279(CHEMBL4869229)
Affinity DataIC50: 212nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574276(CHEMBL4846712)
Affinity DataIC50: 233nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574273(CHEMBL4871853)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574280(CHEMBL4853030)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574269(CHEMBL4857965)
Affinity DataIC50: 563nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574280(CHEMBL4853030)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM117012(US8637532, 739)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50574267(CHEMBL4853114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM116477(US8637532, 158)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM116463(US8637532, 144)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed