Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50017980
TargetAngiotensin-converting enzyme 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606668(CHEMBL5220314)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606669(CHEMBL5220968)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human ACE2 using 7-Mca-YVADAPK (Dnp) as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM21489(MLN4760 | (2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606668(CHEMBL5220314)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606669(CHEMBL5220968)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606670(CHEMBL3219078)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant human ACE2 using fluorogenic peptide substrate VI measured every 36 sec for 10 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606675(CHEMBL3219079)
Affinity DataKi:  0.900nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606676(CHEMBL3219087)
Affinity DataKi:  1nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606671(CHEMBL3219102)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606672(CHEMBL3219101)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606673(CHEMBL3219100)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50606674(CHEMBL3219103)
Affinity DataKi:  3nMAssay Description:Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed