Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50014751
TargetTransthyretin(Human)
University of The Pacific

Curated by ChEMBL
LigandPNGBDBM50579802(CHEMBL5081901)
Affinity DataKd:  516nMAssay Description:Binding affinity to human TTR assessed as binding constant in PBS buffer at pH 7.4 measured after 20 mins fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
University of The Pacific

Curated by ChEMBL
LigandPNGBDBM50579802(CHEMBL5081901)
Affinity DataKd:  851nMAssay Description:Induction of stability of human recombinant interleukin 2 assessed as binding affinity of drug-conjugated rIL2 to human TTR in PBS buffer at pH 7.4 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
University of The Pacific

Curated by ChEMBL
LigandPNGBDBM50579802(CHEMBL5081901)
Affinity DataEC50:  0.609nMAssay Description:Induction of stability of human recombinant interleukin 2 assessed as increase in mouse CTLL-2 cell proliferation measured after 48 hrs by WST-1 assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed