Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015437
TargetBcl-2-like protein 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  2.10nMAssay Description:Displacement of biotin-tagged LWAAQRYGRELRRMSDEFEGSFKGL from human BCL-XL expressed in Escherichia coli measured after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBcl-2-like protein 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586596(CHEMBL5087367)
Affinity DataKd:  7.60nMAssay Description:Displacement of biotin-tagged LWAAQRYGRELRRMSDEFEGSFKGL from human BCL-XL expressed in Escherichia coli measured after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586597(CHEMBL5073297)
Affinity DataKd:  2.80nMAssay Description:Displacement of biotin-tagged LWAAQRYGRELRRMSDEFEGSFKGL from human BCL-XL expressed in Escherichia coli measured after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586598(CHEMBL5077514)
Affinity DataKd:  2.60nMAssay Description:Displacement of biotin-tagged LWAAQRYGRELRRMSDEFEGSFKGL from human BCL-XL expressed in Escherichia coli measured after 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  0.650nMAssay Description:Displacement of biotin-tagged MRPEPATIAQELRRIGDEFNA from C-terminal His-tagged human BCL-2 (1` to 211 residues) expressed in Escherichia coli measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586596(CHEMBL5087367)
Affinity DataKd:  2.30nMAssay Description:Displacement of biotin-tagged MRPEPATIAQELRRIGDEFNA from C-terminal His-tagged human BCL-2 (1` to 211 residues) expressed in Escherichia coli measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586597(CHEMBL5073297)
Affinity DataKd:  1.5nMAssay Description:Displacement of biotin-tagged MRPEPATIAQELRRIGDEFNA from C-terminal His-tagged human BCL-2 (1` to 211 residues) expressed in Escherichia coli measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50586598(CHEMBL5077514)
Affinity DataKd:  1.20nMAssay Description:Displacement of biotin-tagged MRPEPATIAQELRRIGDEFNA from C-terminal His-tagged human BCL-2 (1` to 211 residues) expressed in Escherichia coli measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed