Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50014341
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575153(CHEMBL4866569)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575157(CHEMBL4848450)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575159(CHEMBL4852720)
Affinity DataIC50: 16nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575142(CHEMBL4874476)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575160(CHEMBL4878562)
Affinity DataIC50: 18nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50527193(CHEMBL4471352)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575154(CHEMBL4877677)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575151(CHEMBL4871290)
Affinity DataIC50: 24nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575144(CHEMBL4852619)
Affinity DataIC50: 24nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575155(CHEMBL4870288)
Affinity DataIC50: 24nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575145(CHEMBL4871033)
Affinity DataIC50: 25nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575148(CHEMBL4860780)
Affinity DataIC50: 30nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575150(CHEMBL4876689)
Affinity DataIC50: 31nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575149(CHEMBL4860301)
Affinity DataIC50: 48nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 93nMAssay Description:Inhibition of PDE5A1 (535-860) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 140nMAssay Description:Inhibition of PDE4B2 (152-487) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 260nMAssay Description:Inhibition of PDE10A2 (449-770) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 298nMAssay Description:Inhibition of PDE7A1 (130-482) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575146(CHEMBL4846021)
Affinity DataIC50: 300nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50311741(9-hydroxycalabaxanthone | 1,6-dihydroxy-7-methoxy-...)
Affinity DataIC50: 420nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 440nMAssay Description:Inhibition of PDE1C (147-531) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575147(CHEMBL4855047)
Affinity DataIC50: 494nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 590nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 710nMAssay Description:Inhibition of PDE8A1 (480-828) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 940nMAssay Description:Inhibition of PDE2A (580-919) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575158(CHEMBL4878059)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575143(CHEMBL4858224)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575156(CHEMBL4861275)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE4D2 (86-413) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human hepatic CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (679-1087) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE9A2 (181-506) (unknown origin) expressed in Escherichia coli BL21 assessed as using [3H]-cAMP as substrate measured for 15 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human hepatic CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human hepatic CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human hepatic CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50575152(CHEMBL4877549)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed