Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50017979
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606663(CHEMBL5219543)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606664(CHEMBL1616099)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606665(SYROSINGOPINE | Syrosingopine | Isotense | Londomi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606663(CHEMBL5219543)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606664(CHEMBL1616099)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606665(SYROSINGOPINE | Syrosingopine | Isotense | Londomi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606661(CHEMBL5220706)
Affinity DataIC50: 66nMAssay Description:Inhibition of MCT1 in rat RBE4 cells assessed as reduction in [14C]lactate uptake measured after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 281nMAssay Description:Inhibition of MCT1 in rat RBE4 cells assessed as reduction in [14C]lactate uptake measured after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606666(CHEMBL5219332)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of LAT1 in human MCF7 cells assessed as inhibition of leucine uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Rat)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606662(CHEMBL5221129)
Affinity DataKi:  2.30nMAssay Description:Inhibition of MCT1 in rat erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
Guang Xi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50606667(CHEMBL5220432)
Affinity DataKi:  2.10E+6nMAssay Description:Competitive inhibition of human LAT1 expressed in HEK293 cells assessed as inhibition of L-[14C]-Leucine uptake by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed