Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50015514
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Taipei Chang Gung Memorial Hospital

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of ABCG2 in mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as increase in intracellular mitoxantrone accumu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Taipei Chang Gung Memorial Hospital

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of ABCG2 in becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as increase in intracellular mitoxantrone accumulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed