Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50014707
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579321(CHEMBL4848231)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579322(CHEMBL4877482)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579318(CHEMBL4850546)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579320(CHEMBL4874513)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 11nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579319(CHEMBL4850051)
Affinity DataIC50: 19nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579319(CHEMBL4850051)
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 23nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579318(CHEMBL4850546)
Affinity DataIC50: 24nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579320(CHEMBL4874513)
Affinity DataIC50: 58nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579322(CHEMBL4877482)
Affinity DataIC50: 72nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579321(CHEMBL4848231)
Affinity DataIC50: 303nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579326(CHEMBL4871964)
Affinity DataIC50: 394nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579336(CHEMBL4845823)
Affinity DataIC50: 455nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579323(CHEMBL4878361)
Affinity DataIC50: 528nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579328(CHEMBL4878383)
Affinity DataIC50: 586nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579324(CHEMBL4866788)
Affinity DataIC50: 701nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579325(CHEMBL4850488)
Affinity DataIC50: 887nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579334(CHEMBL4864206)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579327(CHEMBL4847532)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579318(CHEMBL4850546)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation incubated up to 48 hrs under shaking condition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579331(CHEMBL4852099)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579336(CHEMBL4845823)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation incubated up to 48 hrs under shaking condition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579330(CHEMBL4847373)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579329(CHEMBL4863218)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579333(CHEMBL4868597)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579335(CHEMBL4854972)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579323(CHEMBL4878361)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579328(CHEMBL4878383)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579332(CHEMBL4851595)
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579327(CHEMBL4847532)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579334(CHEMBL4864206)
Affinity DataIC50: 4.47E+6nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579331(CHEMBL4852099)
Affinity DataIC50: 6.21E+6nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition and measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579331(CHEMBL4852099)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579329(CHEMBL4863218)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579335(CHEMBL4854972)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579327(CHEMBL4847532)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579332(CHEMBL4851595)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579334(CHEMBL4864206)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579323(CHEMBL4878361)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579328(CHEMBL4878383)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579320(CHEMBL4874513)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579333(CHEMBL4868597)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579321(CHEMBL4848231)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579325(CHEMBL4850488)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50579324(CHEMBL4866788)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO-K1 cell membranes incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
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