Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50014328
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574992(CHEMBL4850135)
Affinity DataKd:  0.0916nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574993(CHEMBL4869660)
Affinity DataKd:  25nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574992(CHEMBL4850135)
Affinity DataKd:  18nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574991(CHEMBL4854774)
Affinity DataKd:  15nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574990(CHEMBL4849327)
Affinity DataKd:  39nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574989(CHEMBL4856941)
Affinity DataKd:  32nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574994(CHEMBL4847620)
Affinity DataKd:  0.0693nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataKd:  0.0935nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574993(CHEMBL4869660)
Affinity DataKd:  0.112nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574991(CHEMBL4854774)
Affinity DataKd:  0.0159nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574990(CHEMBL4849327)
Affinity DataKd:  0.0430nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574989(CHEMBL4856941)
Affinity DataKd:  0.0203nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataKd:  12nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574994(CHEMBL4847620)
Affinity DataKd:  21nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574991(CHEMBL4854774)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574992(CHEMBL4850135)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574994(CHEMBL4847620)
Affinity DataIC50: 11nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 13nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574989(CHEMBL4856941)
Affinity DataIC50: 14nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574993(CHEMBL4869660)
Affinity DataIC50: 15nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProline-rich acidic protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574990(CHEMBL4849327)
Affinity DataIC50: 19nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574991(CHEMBL4854774)
Affinity DataIC50: 37nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed