Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50014821
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580163(CHEMBL5075606)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin stimulated cAMP formation incubated for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin stimulated cAMP formation incubated for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580163(CHEMBL5075606)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580162(CHEMBL5086261)
Affinity DataKi:  260nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580161(CHEMBL5081923)
Affinity DataKi:  380nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580163(CHEMBL5075606)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580161(CHEMBL5081923)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580162(CHEMBL5086261)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2A adenosine receptor expressed in HEK293 cells incubated for 60 mins by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580161(CHEMBL5081923)
Affinity DataKi:  2.39E+3nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2A adenosine receptor expressed in HEK293 cells incubated for 60 mins by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580162(CHEMBL5086261)
Affinity DataKi:  2.45E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed