Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50014692
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579091(CHEMBL4849311)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to GppNHp-bound K-Ras G12V mutant (1 to 185 residues) (unknown origin) expressed in Escherichia coli BL21 cells incubated for 2.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579091(CHEMBL4849311)
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to GDP-bound K-Ras G12V mutant (1 to 185 residues) (unknown origin) expressed in Escherichia coli BL21 cells incubated for 2.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataKd:  1.60nMAssay Description:Displacement of BODIPY-FL-GD from human KRAS G12D (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataKd:  18nMAssay Description:Displacement of BODIPY-FL-GD from human KRAS G12C (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataKd:  42nMAssay Description:Displacement of BODIPY-FL-GD from human wild type KRAS (Met1 to Lys169 residues) incubated for over 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAlbumin(Bovine)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579095(CHEMBL4851139)
Affinity DataKd:  5.70E+4nMAssay Description:Binding affinity to bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579093(CHEMBL4866632)
Affinity DataKd:  22nMAssay Description:Binding affinity to recombinant human KRAS G12D mutant incubated for 0.5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579094(CHEMBL4867496)
Affinity DataKd:  140nMAssay Description:Binding affinity to GppNHp bound His6-tagged KRas G12V mutant (1 to 186 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579095(CHEMBL4851139)
Affinity DataKd:  230nMAssay Description:Binding affinity to GDP bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579095(CHEMBL4851139)
Affinity DataKd:  21nMAssay Description:Binding affinity to GppNHp bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579095(CHEMBL4851139)
Affinity DataKd:  42nMAssay Description:Binding affinity to GTPgammaS bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579091(CHEMBL4849311)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to GTP-bound K-Ras G12V mutant (1 to 185 residues) (unknown origin) expressed in Escherichia coli BL21 cells incubated for 2.5 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579094(CHEMBL4867496)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579129(CHEMBL4849298)
Affinity DataIC50: 230nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579128(CHEMBL4860021)
Affinity DataIC50: 280nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579123(CHEMBL4874865)
Affinity DataIC50: 330nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579124(CHEMBL4860310)
Affinity DataIC50: 410nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579122(CHEMBL4870167)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579114(CHEMBL4856294)
Affinity DataIC50: 510nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579131(CHEMBL4869131)
Affinity DataIC50: 520nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579145(CHEMBL4850331)
Affinity DataIC50: 550nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579111(CHEMBL4870843)
Affinity DataIC50: 550nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579147(CHEMBL4849460)
Affinity DataIC50: 560nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579134(CHEMBL4864561)
Affinity DataIC50: 560nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579150(CHEMBL4854699)
Affinity DataIC50: 570nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579149(CHEMBL4872691)
Affinity DataIC50: 610nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579132(CHEMBL4852857)
Affinity DataIC50: 610nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579138(CHEMBL4869496)
Affinity DataIC50: 640nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579130(CHEMBL4845665)
Affinity DataIC50: 650nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579095(CHEMBL4851139)
Affinity DataIC50: 690nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579112(CHEMBL4876249)
Affinity DataIC50: 700nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579117(CHEMBL4872610)
Affinity DataIC50: 700nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579110(CHEMBL4871362)
Affinity DataIC50: 700nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579139(CHEMBL4872844)
Affinity DataIC50: 710nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579146(CHEMBL4879058)
Affinity DataIC50: 710nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579148(CHEMBL4859210)
Affinity DataIC50: 710nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579144(CHEMBL4874466)
Affinity DataIC50: 750nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579151(CHEMBL4852330)
Affinity DataIC50: 750nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579121(CHEMBL4870215)
Affinity DataIC50: 760nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579118(CHEMBL4851141)
Affinity DataIC50: 770nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579133(CHEMBL4862082)
Affinity DataIC50: 790nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579137(CHEMBL4864250)
Affinity DataIC50: 830nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579140(CHEMBL4869530)
Affinity DataIC50: 860nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579127(CHEMBL4852356)
Affinity DataIC50: 870nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579109(CHEMBL4863190)
Affinity DataIC50: 890nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579120(CHEMBL4877546)
Affinity DataIC50: 940nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579143(CHEMBL4848941)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579116(CHEMBL4847834)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579135(CHEMBL4847131)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50579125(CHEMBL4871622)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
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