Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50014542
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50240609(CHEMBL1016 | 2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-bip...)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50049186(CHEMBL1069 | (S)-3-Methyl-2-{pentanoyl-[2'-(1H-tet...)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042234(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataEC50:  6.58E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042251(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-y...)
Affinity DataEC50:  860nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577226(CHEMBL4872989)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577227(CHEMBL4856425)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042250(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmeth...)
Affinity DataEC50:  2.42E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577228(CHEMBL4859498)
Affinity DataEC50:  6.39E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577229(CHEMBL4877651)
Affinity DataEC50:  8.14E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577230(CHEMBL4854916)
Affinity DataEC50:  7.50E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577226(CHEMBL4872989)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577227(CHEMBL4856425)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577229(CHEMBL4877651)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042251(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-y...)
Affinity DataIC50: 155nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042234(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577228(CHEMBL4859498)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577231(CHEMBL4868159)
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042250(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmeth...)
Affinity DataIC50: 7.75E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 8.65E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042263(4'-(4-Oxo-2-phenyl-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Fraunhofer Institute For Translational Medicine and Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50577230(CHEMBL4854916)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed