Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50018659
TargetProtein cereblon(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50610870(CHEMBL5272173)
Affinity DataKd:  490nMAssay Description:Binding affinity to CRBN (unknown origin) by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50610869(CHEMBL5288938)
Affinity DataIC50: 2nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50610869(CHEMBL5288938)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Akt3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRAC-beta serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50610869(CHEMBL5288938)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Akt2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Akt3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRAC-beta serine/threonine-protein kinase(Human)
The Affiliated Hospital of Qingdao University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Akt2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)