Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50018283
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410642(CHEMBL5287722)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410643(CHEMBL5289030)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410568(CHEMBL5287991)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM412136(US10392402, Compound A | US10738007, Compound A | ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50324574((R)-6-Methoxy-N-(2-((1-methylpiperidin-4-yl)methox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM412136(US10392402, Compound A | US10738007, Compound A | ...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410568(CHEMBL5287991)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM14047(N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM14047(N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410567(CHEMBL5266198)
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410567(CHEMBL5266198)
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410783(BELUMOSUDIL)
Affinity DataIC50: 105nMAssay Description:Inhibition of human ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 720nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50027431(Hydroxy-Fasudil | HYDROXYFASUDIL)
Affinity DataIC50: 720nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410569(CHEMBL5278924)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410569(CHEMBL5278924)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50410783(BELUMOSUDIL)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed