Compile Data Set for Download or QSAR
Report error Found 120 Enz. Inhib. hit(s) with all data for entry = 50018656
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM21998(6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM21998(6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610832(CHEMBL5282741)
Affinity DataIC50: 13nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610830(CHEMBL5267752)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 21nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataIC50: 22nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610863(CHEMBL5280923)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610851(CHEMBL5290111)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610837(CHEMBL5281492)
Affinity DataIC50: 62nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610836(MSC-4381)
Affinity DataIC50: 77nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610830(CHEMBL5267752)
Affinity DataIC50: 79nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610835(CHEMBL5267349)
Affinity DataIC50: 80nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610834(CHEMBL5279064)
Affinity DataIC50: 92nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610833(CHEMBL5276884)
Affinity DataIC50: 99nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610818(CHEMBL5284913)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610853(CHEMBL5291399)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610833(CHEMBL5276884)
Affinity DataIC50: 137nMAssay Description:Inhibition of human MCT4 in human NCI-H358 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610826(CHEMBL5287351)
Affinity DataIC50: 139nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610827(CHEMBL5287780)
Affinity DataIC50: 154nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610847(CHEMBL5280358)
Affinity DataIC50: 200nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610850(CHEMBL5278014)
Affinity DataIC50: 200nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610824(CHEMBL5268966)
Affinity DataIC50: 215nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610833(CHEMBL5276884)
Affinity DataIC50: 239nMAssay Description:Inhibition of human MCT4 in human NCI-H441 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610864(CHEMBL5268302)
Affinity DataIC50: 240nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610829(CHEMBL5288904)
Affinity DataIC50: 243nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610820(CHEMBL5289504)
Affinity DataIC50: 300nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610854(CHEMBL5274725)
Affinity DataIC50: 300nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610846(CHEMBL5291036)
Affinity DataIC50: 400nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610831(CHEMBL5265956)
Affinity DataIC50: 490nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610797(CHEMBL5289665)
Affinity DataIC50: 500nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610865(CHEMBL5284412)
Affinity DataIC50: 570nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610825(CHEMBL5266104)
Affinity DataIC50: 579nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610796(CHEMBL5280178)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610844(CHEMBL5266150)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610845(CHEMBL5281466)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610849(CHEMBL5282350)
Affinity DataIC50: 700nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610819(CHEMBL5285385)
Affinity DataIC50: 800nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610848(CHEMBL5280269)
Affinity DataIC50: 800nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610838(CHEMBL5271238)
Affinity DataIC50: 900nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610866(CHEMBL5279333)
Affinity DataIC50: 960nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610836(MSC-4381)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610855(CHEMBL5272725)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610828(CHEMBL5271816)
Affinity DataIC50: 1.02E+3nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610808(CHEMBL5286769)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610815(CHEMBL5272951)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610822(CHEMBL5289345)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610812(CHEMBL5286036)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610807(CHEMBL5281759)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
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