Compile Data Set for Download or QSAR
Report error Found 229 Enz. Inhib. hit(s) with all data for entry = 50018700
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50320082(1-(4-Amino-2-butyl-1H-imidazo-[4,5-c]quinolin-1-yl...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50330062(1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  363nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50320082(1-(4-Amino-2-butyl-1H-imidazo-[4,5-c]quinolin-1-yl...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50330062(1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611560(CHEMBL5279460)
Affinity DataEC50:  192nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611561(CHEMBL5273836)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611562(CHEMBL5274930)
Affinity DataEC50:  323nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611563(CHEMBL5266081)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611564(CHEMBL5280339)
Affinity DataEC50:  433nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611565(CHEMBL5281346)
Affinity DataEC50:  136nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611566(CHEMBL5284650)
Affinity DataEC50:  787nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611567(CHEMBL5284156)
Affinity DataEC50:  247nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611568(CHEMBL5278820)
Affinity DataEC50:  169nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611569(CHEMBL5279345)
Affinity DataEC50:  633nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611570(CHEMBL5280038)
Affinity DataEC50:  904nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611571(CHEMBL5284794)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611572(CHEMBL5265869)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611573(CHEMBL5290305)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611574(CHEMBL5268126)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611575(CHEMBL5268896)
Affinity DataEC50:  168nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611576(CHEMBL5280737)
Affinity DataEC50:  235nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611577(CHEMBL5290635)
Affinity DataEC50:  139nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611578(CHEMBL5272247)
Affinity DataEC50:  297nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611579(CHEMBL5284200)
Affinity DataEC50:  156nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611580(CHEMBL5269862)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611581(CHEMBL5267507)
Affinity DataEC50:  105nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611582(CHEMBL5281712)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611583(CHEMBL5269759)
Affinity DataEC50:  181nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611584(CHEMBL5266430)
Affinity DataEC50:  349nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611585(CHEMBL5289435)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611586(CHEMBL5272344)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611587(CHEMBL5268141)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611588(CHEMBL5281238)
Affinity DataEC50:  172nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611589(CHEMBL5287206)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611590(CHEMBL5284004)
Affinity DataEC50:  177nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611591(CHEMBL5269882)
Affinity DataEC50:  243nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611592(CHEMBL5267974)
Affinity DataEC50:  137nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611593(CHEMBL5272502)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611594(CHEMBL5281073)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611595(CHEMBL5267937)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611596(CHEMBL5280107)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611597(CHEMBL5279923)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611598(CHEMBL5273317)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611599(CHEMBL5266058)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611600(CHEMBL5283748)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50611601(CHEMBL5269286)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human TLR7 transfected in HEK293 cells assessed as induction of SEAP production incubated overnight by SEAP reporter gene based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
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