Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50014811
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580117(CHEMBL5076176)
Affinity DataIC50: 190nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580113(CHEMBL5090659)
Affinity DataIC50: 690nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580116(CHEMBL5093943)
Affinity DataIC50: 780nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580121(CHEMBL5085594)
Affinity DataIC50: 780nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580115(CHEMBL5084848)
Affinity DataIC50: 910nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580112(CHEMBL5077748)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580120(CHEMBL5077920)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580122(CHEMBL5074925)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580121(CHEMBL5085594)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580120(CHEMBL5077920)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580119(CHEMBL5082640)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580118(CHEMBL5094059)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580117(CHEMBL5076176)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580116(CHEMBL5093943)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580115(CHEMBL5084848)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580114(CHEMBL5075801)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580113(CHEMBL5090659)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580112(CHEMBL5077748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580122(CHEMBL5074925)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580119(CHEMBL5082640)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580118(CHEMBL5094059)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50580114(CHEMBL5075801)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed