Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50014809
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  5.97E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  1.92E+4nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580105(CHEMBL5086989)
Affinity DataEC50:  1.66E+4nMAssay Description:Inverse agonist at human GPR17 in human LN-229 cells assessed as intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580105(CHEMBL5086989)
Affinity DataEC50:  1.77E+4nMAssay Description:Inverse agonist at human GPR17 in human SNB-19 cells assessed as intracellular cAMP levels incubated for 2 hrs by cAMP Glo Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580105(CHEMBL5086989)
Affinity DataEC50:  2.69E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  4.19E+4nMAssay Description:Agonist activity at human GPR17 in human LN-229 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580105(CHEMBL5086989)
Affinity DataEC50:  2.63E+4nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Tampere University

Curated by ChEMBL
LigandPNGBDBM50580104(CHEMBL5083629)
Affinity DataEC50:  7.67E+3nMAssay Description:Agonist activity at human GPR17 in human SNB-19 cells assessed as decrease in calcium ion levels incubated for 2 hrs by Calcium Fura 2 Dynamic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed