Compile Data Set for Download or QSAR
Report error Found 202 Enz. Inhib. hit(s) with all data for entry = 50014670
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM506627(US11046649, Ex. 5)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578624(CHEMBL4856710)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578623(CHEMBL4858888)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578677(CHEMBL4849690)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578623(CHEMBL4858888)
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578635(CHEMBL4875089)
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578639(CHEMBL4868112)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578625(CHEMBL4855340)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578633(CHEMBL4872522)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578622(CHEMBL4861332)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578624(CHEMBL4856710)
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578649(CHEMBL4866113)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578650(CHEMBL4866976)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578666(CHEMBL4859064)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578666(CHEMBL4859064)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578668(CHEMBL4863359)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM506659(US11046649, Ex. 37 | 4-chloro-N-((R)-cyclo- propyl...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578672(CHEMBL4869547)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578655(CHEMBL4856417)
Affinity DataIC50: 4nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578638(CHEMBL4873928)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578673(CHEMBL4853672)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578656(CHEMBL4858219)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578651(CHEMBL4866916)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578674(CHEMBL4849414)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578625(CHEMBL4855340)
Affinity DataIC50: 5.80nMAssay Description:In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice da...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578634(CHEMBL4846874)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578643(CHEMBL4854742)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578654(CHEMBL4852566)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578647(CHEMBL4878766)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578642(CHEMBL4853036)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578648(CHEMBL4873803)
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578653(CHEMBL4872039)
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578675(CHEMBL4845961)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578644(CHEMBL4848111)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578678(CHEMBL4871068)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578669(CHEMBL4848514)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578627(CHEMBL4872488)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578667(CHEMBL4864639)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578632(CHEMBL4852532)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578657(CHEMBL4862584)
Affinity DataIC50: 12nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578622(CHEMBL4861332)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM370555(US10233190, Example 1488 | (1R,4r)-4-((R)-2-((S)-6...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM370555(US10233190, Example 1488 | (1R,4r)-4-((R)-2-((S)-6...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578637(CHEMBL4872803)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578624(CHEMBL4856710)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in human whole blood stimulated with IFNgamma/LPS using L-tryptophan/kynurenine as substrate incubated for 15 mins followed by IFN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578640(CHEMBL4873892)
Affinity DataIC50: 18nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578645(CHEMBL4865079)
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578662(CHEMBL4861936)
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Displayed 1 to 50 (of 202 total ) | Next | Last >>
Jump to: