Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50018099
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403301(CHEMBL4289676)
Affinity DataKd:  210nMAssay Description:Binding affinity to human MDM4 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403526(CHEMBL5286722)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403367(CHEMBL5283428)
Affinity DataKd:  43nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403367(CHEMBL5283428)
Affinity DataKd:  25nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403526(CHEMBL5286722)
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403527(CHEMBL5280949)
Affinity DataKd:  27nMAssay Description:Inhibition of human his-tagged MDM4 assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403367(CHEMBL5283428)
Affinity DataKd:  149nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403306(CHEMBL5271788)
Affinity DataKd:  13nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403305(CHEMBL5275075)
Affinity DataKd:  229nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50437206(CHEMBL2402737 | US20250073340, Example RG7388)
Affinity DataKd: <100nMAssay Description:Inhibition of MDM4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403306(CHEMBL5271788)
Affinity DataKd:  12nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403305(CHEMBL5275075)
Affinity DataKd:  216nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403301(CHEMBL4289676)
Affinity DataKd:  600nMAssay Description:Binding affinity to human MDM2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM6863(US8815926, 101 | US8815926, 295)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human MDM4 by SRP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM6863(US8815926, 101 | US8815926, 295)
Affinity DataIC50: 0.210nMAssay Description:Binding affinity to human MDM2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403302(CHEMBL5290323)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity to human MDM2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403528(CHEMBL5280843)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity against human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50: 20nMAssay Description:Inhibition of human MDM2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 25nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 33nMAssay Description:Inhibition of human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 41nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403303(CHEMBL5273706)
Affinity DataIC50: 44nMAssay Description:Inhibition of human MDM2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403304(CHEMBL5268770)
Affinity DataIC50: 110nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403529(CHEMBL5290391)
Affinity DataIC50: 145nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403303(CHEMBL5273706)
Affinity DataIC50: 550nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM6863(US8815926, 101 | US8815926, 295)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to human MDM4 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403530(CHEMBL5267194)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403530(CHEMBL5267194)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403302(CHEMBL5290323)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to human MDM4 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403372(CHEMBL5286157)
Affinity DataKi:  7.70nMAssay Description:Binding affinity to human MDM2 assessed as inhibition constant by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403372(CHEMBL5286157)
Affinity DataKi:  25nMAssay Description:Binding affinity to human MDM4 assessed as inhibition constant by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50014089(CHEMBL1236726)
Affinity DataKi:  109nMAssay Description:Binding affinity to human MDM2 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403369(CHEMBL5271133)
Affinity DataKi:  620nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403369(CHEMBL5271133)
Affinity DataKi:  620nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403368(CHEMBL5290720)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50014089(CHEMBL1236726)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to human MDM4 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  3.60E+4nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403369(CHEMBL5271133)
Affinity DataKi:  5.40E+4nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403368(CHEMBL5290720)
Affinity DataKi:  5.40E+4nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKi:  6.90E+4nMAssay Description:Binding affinity to human MDM4 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKi:  7.00E+4nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)