Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50017412
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601687(CHEMBL5192551)
Affinity DataKd:  9.10E+3nMAssay Description:Binding affinity to full length His-tagged DENV-2 NS5 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50350203(CHEMBL1814771)
Affinity DataIC50: 500nMAssay Description:Inhibition of Zika virus RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 750nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601689(CHEMBL5180295)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Zika virus wild type RNA-dependent RNA polymerase using ATP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of Zika virus RNA-dependent RNA polymerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601687(CHEMBL5192551)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length His-tagged DENV-2 NS5 incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601688(CHEMBL5199491)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of full length His-tagged DENV-2 NS5 incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of DENV-2 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of DENV-4 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50478971(2''C-Me-ATP | CHEMBL374931)
Affinity DataIC50: 5.26E+3nMAssay Description:Inhibition of Zika virus RNA-dependent RNA polymerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601690(CHEMBL2057532)
Affinity DataIC50: 8.92E+3nMAssay Description:Inhibition of Zika virus RNA-dependent RNA polymerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525250(CHEMBL4526128)
Affinity DataIC50: 9.61E+3nMAssay Description:Inhibition of DENV-2 DENV2 NS2B-NS3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601686(CHEMBL5182967)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of DENV-4 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601685(CHEMBL5205786)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of DENV-4 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed