Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50014035
LigandPNGBDBM50571960(CHEMBL4848983)
Affinity DataIC50: 370nMAssay Description:Inhibition of human PDHK1 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571960(CHEMBL4848983)
Affinity DataIC50: 590nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571963(CHEMBL4855768)
Affinity DataIC50: 710nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571969(CHEMBL4870933)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571964(CHEMBL4867063)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571962(CHEMBL4862550)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571965(CHEMBL4870403)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50571961(CHEMBL4877843)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571959(CHEMBL4850127)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571963(CHEMBL4855768)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571969(CHEMBL4870933)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571960(CHEMBL4848983)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human PDHK3 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571967(CHEMBL4870610)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571958(CHEMBL4857154)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571964(CHEMBL4867063)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571962(CHEMBL4862550)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571965(CHEMBL4870403)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571960(CHEMBL4848983)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50571966(CHEMBL4848708)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571971(CHEMBL4847931)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571966(CHEMBL4848708)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571967(CHEMBL4870610)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571972(CHEMBL4860270)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571971(CHEMBL4847931)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571972(CHEMBL4860270)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571968(CHEMBL4876923)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571959(CHEMBL4850127)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human PDHK2 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571968(CHEMBL4876923)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50428378(Methyl 2,4-Dihydroxybenzoate | CHEMBL486026)
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibition of human PDHK2 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 2.79E+5nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571970(CHEMBL4847005)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571970(CHEMBL4847005)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571958(CHEMBL4857154)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571961(CHEMBL4877843)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571963(CHEMBL4855768)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human recombinant BCKDK incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50428378(Methyl 2,4-Dihydroxybenzoate | CHEMBL486026)
Affinity DataIC50: 3.45E+5nMAssay Description:Inhibition of human PDHK4 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 8.90E+5nMAssay Description:Inhibition of human PDHK4 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50434120(OXINDOLE)
Affinity DataIC50: 9.58E+5nMAssay Description:Inhibition of human PDHK2 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50434120(OXINDOLE)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human PDHK4 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)