Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50014463
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167602(US9073922, 87 | US9796708, Example 87)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167602(US9073922, 87 | US9796708, Example 87)
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167728(US9073922, 215 | US9796708, Example 215)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM351938(ethyl ({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167738(US9073922, 226 | US9796708, Example 226)
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167615(US9073922, 101 | US9796708, Example 101)
Affinity DataIC50: 36nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167633(US9073922, 119 | US9796708, Example 119)
Affinity DataIC50: 43nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353391(N-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354119(cis-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[...)
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167615(US9073922, 101 | US9796708, Example 101)
Affinity DataIC50: 72nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167732(US9073922, 219 | US9796708, Example 219)
Affinity DataIC50: 75nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50576480(CHEMBL4857987)
Affinity DataIC50: 75nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354126(trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167797(US9073922, 288 | US9796708, Example 288)
Affinity DataIC50: 80nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354125(cis-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H...)
Affinity DataIC50: 81nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354120(trans-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrol...)
Affinity DataIC50: 83nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354123((1-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 86nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167738(US9073922, 226 | US9796708, Example 226)
Affinity DataIC50: 87nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353373(4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 89nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167751(US9073922, 241 | US9796708, Example 241)
Affinity DataIC50: 91nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354122((trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354125(cis-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354126(trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353291((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167728(US9073922, 215 | US9796708, Example 215)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354121((cis-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50576479(CHEMBL4878465)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354065((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354122((trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354107((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354121((cis-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1...)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167798(US9073922, 289 | US9796708, Example 289)
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate measured after 1.5 hrs by TR-FRET LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM351938(ethyl ({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354119(cis-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167797(US9073922, 288 | US9796708, Example 288)
Affinity DataIC50: 220nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167633(US9073922, 119 | US9796708, Example 119)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354120(trans-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrol...)
Affinity DataIC50: 270nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167798(US9073922, 289 | US9796708, Example 289)
Affinity DataIC50: 350nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167751(US9073922, 241 | US9796708, Example 241)
Affinity DataIC50: 370nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354065((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 640nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353373(4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 660nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50576479(CHEMBL4878465)
Affinity DataIC50: 680nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354123((1-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 980nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353291((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM353391(N-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM167732(US9073922, 219 | US9796708, Example 219)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM354107((4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed