Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50014461
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576473(CHEMBL4870936)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576474(CHEMBL4849957)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576477(CHEMBL4850118)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576475(CHEMBL4878670)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576476(CHEMBL4850085)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576473(CHEMBL4870936)
Affinity DataIC50: 1nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576477(CHEMBL4850118)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576475(CHEMBL4878670)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576478(CHEMBL4863896)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human TLR8 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576474(CHEMBL4849957)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576476(CHEMBL4850085)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576478(CHEMBL4863896)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human TLR7 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576474(CHEMBL4849957)
Affinity DataIC50: 53nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576478(CHEMBL4863896)
Affinity DataIC50: 57nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576476(CHEMBL4850085)
Affinity DataIC50: 106nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576473(CHEMBL4870936)
Affinity DataIC50: 118nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576475(CHEMBL4878670)
Affinity DataIC50: 121nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576477(CHEMBL4850118)
Affinity DataIC50: 139nMAssay Description:Inhibition of human TLR9 expressed in HEK293-Blue cells assessed as inhibition of R848-induced NF-kappaB/AP-1 activation measured after 20 hrs using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed