Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50018096
Affinity DataEC50: 160nMAssay Description:Inverse agonist activity at human RORgammat LBD (265 to 507 residues) expressed in sf9 cells assessed as corepressor peptide recruiting activity by F...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at His tagged human RORgammat incubated for 1 hrs in presence of biotinylated co-activator peptide by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inverse agonist activity at His tagged RORgammat (unknown origin) incubated for 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inverse agonist activity against human RORgammat by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inverse agonist activity against human RORgammat by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) incubated for 20 mins by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Allosteric inverse agonist at His tagged RORgammat (unknown origin) expressed in Escherichia coli BL21(DE3) cells incubated for 2 hrs by TR-FRET assa...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at His tagged human RORgammat incubated for 1 hrs in presence of biotinylated co-activator peptide by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity against human RORgammat assessed as IL-17 secretion by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inverse agonist activity at human RORgammat LBD expressed in Jurkat cells incubated for 24 hrs by Gal4 luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inverse agonist activity against human RORgammat assessed as IL-17 secretion incubated for 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibition of human IL-17 by whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of 25-[26,27-3H2]-hydroxycholesterol from RORgammat (unknown origin) assessed as inhibition constant by scintillation proximity assayMore data for this Ligand-Target Pair
